BEBT-109, A PAN-MUTANT-SELECTIVE EGFR INHIBITOR WITH POTENT ANTITUMOR ACTIVITY IN EGFR-MUTANT NON-SMALL CELL LUNG CANCER

BEBT-109, a pan-mutant-selective EGFR inhibitor with potent antitumor activity in EGFR-mutant non-small cell lung cancer

EGFR mutation-positive NSCLC tumors are highly heterogeneous, therefore, exploring an agent simultaneously targeting multiple EGFR guerlain ideal cologne mutations may be valuable for clinical practice.Compared with osimertinib, BEBT-109 shows more sensitive and extensive antitumor activity in EGFR mutant NSCLC, while sparing wild-type EGFR cell li

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An Ontology-Based Framework for Geospatial Integration and Querying of Raster Data Cube Using Virtual Knowledge Graphs

The integration of the raster data cube alongside another form of geospatial data (e.g., vector data) raises considerable challenges when it comes to managing and representing it using knowledge graphs.Such integration can play an invaluable role in handling the heterogeneity of geospatial data and linking the raster data cube to semantic technolog

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Measurement system as a subsystem of the quality management system

Each measurement system and a control principle must be based on certain facts about outdoor round junction box for 3 screw base cameras the system behaviour (what), operation (how) and structure (why).Each system is distributed into subsystems that provide an input for the next subsystem.For each system, start is important the begin, that means sy

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TRC210258, a novel TGR5 agonist, reduces glycemic and dyslipidemic cardiovascular risk in animal models of diabesity

Shitalkumar P Zambad, Davinder Tuli, Anoop Mathur, Sameer A Ghalsasi, Anita R Chaudhary, Shailesh Deshpande, Ramesh C Gupta, Vijay Chauthaiwale, Chaitanya DuttTorrent Research Centre, Torrent Pharmaceuticals Ltd, Gujarat, sepia plex IndiaBackground: Patients with diabesity have a significantly increased risk of developing cardiovascular diseas

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